Which pancreatic hormone raises blood glucose levels?

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Multiple Choice

Which pancreatic hormone raises blood glucose levels?

The main idea is that glucagon is the hormone that raises blood glucose. It’s released by the pancreatic alpha cells when blood sugar is low. Once in the liver, glucagon stimulates glycogenolysis (breaking down stored glycogen) and gluconeogenesis (making new glucose), which increases the amount of glucose released into the bloodstream. This is how the body quickly restores normal glucose levels during hypoglycemia. In contrast, insulin lowers blood glucose by promoting uptake and storage of glucose in liver, muscle, and fat tissue, and by stimulating glycolysis and glycogen synthesis. Somatostatin primarily acts to dampen the release of insulin and glucagon, so it doesn’t raise glucose by itself. Amylin works with insulin to regulate postprandial glucose, mainly by slowing gastric emptying and suppressing glucagon, which helps blunt glucose spikes rather than raise them.

The main idea is that glucagon is the hormone that raises blood glucose. It’s released by the pancreatic alpha cells when blood sugar is low. Once in the liver, glucagon stimulates glycogenolysis (breaking down stored glycogen) and gluconeogenesis (making new glucose), which increases the amount of glucose released into the bloodstream. This is how the body quickly restores normal glucose levels during hypoglycemia.

In contrast, insulin lowers blood glucose by promoting uptake and storage of glucose in liver, muscle, and fat tissue, and by stimulating glycolysis and glycogen synthesis. Somatostatin primarily acts to dampen the release of insulin and glucagon, so it doesn’t raise glucose by itself. Amylin works with insulin to regulate postprandial glucose, mainly by slowing gastric emptying and suppressing glucagon, which helps blunt glucose spikes rather than raise them.

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