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Multiple Choice

What measure reflects kidney filtration function?

Glomerular filtration rate measures how fast plasma is filtered by the kidneys’ glomeruli each minute, which directly reflects the kidneys’ filtering capacity. Because it quantifies the actual filtration process, GFR best represents kidney function. Urine output only tells you how much urine is being produced and can be influenced by hydration, fluids, or obstruction, not by the efficiency of filtration itself. BUN and serum creatinine are waste products whose levels echo filtration indirectly, but they’re affected by many other factors—protein intake, liver function, hydration, muscle mass—so they don’t alone measure filtration capacity. In clinical practice, GFR is estimated from serum creatinine (with adjustments for age, sex, and body size) or measured with more precise methods; it provides a direct sense of filtration function. Normal GFR is about 90–120 mL/min, and decreases indicate reduced filtration.

Glomerular filtration rate measures how fast plasma is filtered by the kidneys’ glomeruli each minute, which directly reflects the kidneys’ filtering capacity. Because it quantifies the actual filtration process, GFR best represents kidney function. Urine output only tells you how much urine is being produced and can be influenced by hydration, fluids, or obstruction, not by the efficiency of filtration itself. BUN and serum creatinine are waste products whose levels echo filtration indirectly, but they’re affected by many other factors—protein intake, liver function, hydration, muscle mass—so they don’t alone measure filtration capacity. In clinical practice, GFR is estimated from serum creatinine (with adjustments for age, sex, and body size) or measured with more precise methods; it provides a direct sense of filtration function. Normal GFR is about 90–120 mL/min, and decreases indicate reduced filtration.