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Multiple Choice

Minute ventilation is calculated as which of the following?

Minute ventilation reflects the total amount of air moving in and out of the lungs each minute. It’s found by multiplying the amount of air moved with each breath (tidal volume) by how many breaths are taken each minute (respiratory rate). So, VE = VT × f. This tells you the overall air flow, regardless of where the air goes. It’s helpful to distinguish this from alveolar ventilation, which is the portion of air that actually reaches the gas-exchange areas. Alveolar ventilation accounts only for the air that participates in gas exchange and is calculated as (tidal volume minus dead space) times the respiratory rate. Dead space is the part of each breath that doesn’t reach the alveoli. For example, if tidal volume is 500 mL and the rate is 12 breaths per minute, minute ventilation is 6,000 mL per minute (6 L/min). If dead space is about 150 mL, alveolar ventilation would be (500 − 150) × 12 = 4,200 mL per minute (4.2 L/min). Multiplying respiratory rate by alveolar dead space (12 × 150) would not give either of these ventilation measures, so it isn’t used to calculate minute ventilation.

Minute ventilation reflects the total amount of air moving in and out of the lungs each minute. It’s found by multiplying the amount of air moved with each breath (tidal volume) by how many breaths are taken each minute (respiratory rate). So, VE = VT × f. This tells you the overall air flow, regardless of where the air goes.

It’s helpful to distinguish this from alveolar ventilation, which is the portion of air that actually reaches the gas-exchange areas. Alveolar ventilation accounts only for the air that participates in gas exchange and is calculated as (tidal volume minus dead space) times the respiratory rate. Dead space is the part of each breath that doesn’t reach the alveoli.

For example, if tidal volume is 500 mL and the rate is 12 breaths per minute, minute ventilation is 6,000 mL per minute (6 L/min). If dead space is about 150 mL, alveolar ventilation would be (500 − 150) × 12 = 4,200 mL per minute (4.2 L/min). Multiplying respiratory rate by alveolar dead space (12 × 150) would not give either of these ventilation measures, so it isn’t used to calculate minute ventilation.