In the anatomical position, the heart is located in which mediastinal region?

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In this context, the heart sits in the middle mediastinum, which is the central portion of the inferior mediastinum. The inferior mediastinum is divided into anterior, middle, and posterior parts, and the heart and its pericardial sac occupy the middle compartment. The heart lies anterior to the posterior mediastinal structures and posterior to the sternum, with the superior mediastinum above and the anterior mediastinum in front of it. The term retrosternal isn’t a standard designation for the heart’s location; the space behind the sternum isn’t where the heart resides—the heart is in the middle mediastinum.